evidence-based information about mifepristone, methotrexate & misoprostol

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legal status of abortion worldwide



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Welcome to the medication abortion website operated by Ibis Reproductive Health. This site is designed to provide medically accurate and evidence-based information about medication abortion to researchers and health service providers, including physicians, nurse practitioners, physician assistants, midwives, counselors, community health workers, and office staff. Educational information is also provided for women considering the option of medication abortion.

Information contained in this website is derived from literature published in international medical journals. The content of the website has been reviewed by experts in the field and is updated periodically.

Since the launch of the website in 2003, has become a global resource. The website receives more than a million visitors a year from over 200 countries and territories. We have optimized this text heavy website to accomodate users in low resource settings.

This site was last updated January 2015.

What is medication abortion?


Medication abortion, also known as medical abortion, the abortion pill, non-aspiration, or non-surgical abortion, refers to a family of safe and effective methods for terminating an unwanted pregnancy. Through the use of a drug or combination of drugs that are administered orally, vaginally, buccally, sublingually, and/or intramuscularly, medication abortion causes the pregnancy to terminate and the uterus to expel the products of conception. Worldwide, three methods of medication abortion are in practice for early pregnancy termination:

Mifepristone & misoprostol
Methotrexate & misoprostol
Misoprostol alone



If you have questions about medication abortion, please visit our frequently asked questions section.

This month’s featured question

I am 22 years old and I am from Peru. Abortion is very restricted in my country but I was able to get misoprostol pills from a pharmacy in my town. I am planning on taking the first dose tomorrow. What kind of bleeding will I have after I take the pills? My last period started seven weeks ago.

Click here to read the response to the featured question.

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About Ibis Reproductive Health

Ibis Reproductive Health is an international nonprofit organization with a mission to improve women’s reproductive autonomy, choices, and health worldwide. Our core activity is clinical and social science research, focused on issues receiving inadequate attention in other research settings and where gaps in the evidence exist. Our agenda is driven by women’s needs and prioritizes increasing access to safe abortion, expanding contraceptive access and choices, and integrating HIV and comprehensive sexual and reproductive health services. We partner with advocates and other stakeholders who use our research to improve policies and delivery of services in countries around the world. To learn more about Ibis, please visit the Ibis website (English only).

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