Who should not use medication abortion?

Medication abortion methods may be contraindicated if a woman suffers from specific conditions or diseases. The following table provides a list of contraindications (by medication abortion method).

Mifepristone/Misoprostol	Methotrexate/Misoprostol	Misoprostol Alone
Confirmed or suspected ectopic pregnancy Allergy to mifepristone Allergy to misoprostol Chronic systemic use of corticosteroids Coagulopathy Current anticoagulant therapy Chronic adrenal failure Inherited porphyries IUD in situ (must be removed prior to induction)	Allergy to methotrexate Allergy to misoprostol Coagulopathy Severe anemia Acute or chronic renal disease Acute or chronic hepatic disease Acute inflammatory bowel disease Uncontrolled seizure disorders IUD in situ (must be removed prior to induction)	Allergy to misoprostol Uterine/genital infection* Coagulopathy* Hypertension* Severe Anemia* Cardiovascular disease* Cerebrovascular disease* IUD in situ (must be removed prior to induction) * women with these conditions were excluded from clinical studies and may not be eligible for the misoprostol-only regimen