Who should not use medication abortion?

Most women who have an unwanted pregnancy of nine weeks or less are eligible for medication abortion methods. Medication abortion methods may be contraindicated if a woman suffers from specific conditions or diseases, listed on the table below. Women who have any of these conditions should discuss their eligibility for medication abortion and their abortion care options with their health care provider.

Mifepristone and misoprostol
Methotrexate and misoprostol
Misoprostol alone
  • Confirmed or suspected ectopic pregnancy
  • Allergy to mifepristone
  • Allergy to misoprostol
  • Chronic systemic use of corticosteroids
  • Coagulopathy
  • Current anticoagulant therapy
  • Chronic adrenal failure
  • Inherited porphyries
  • IUD in situ (must be removed prior to induction)
  • Allergy to methotrexate
  • Allergy to misoprostol
  • Coagulopathy
  • Severe anemia
  • Acute or chronic renal disease
  • Acute or chronic hepatic disease
  • Acute inflammatory bowel disease
  • Uncontrolled seizure disorders
  • IUD in situ (must be removed prior to induction)
  • Allergy to misoprostol
  • IUD in situ (must be removed prior to induction)

In addition, women with the following conditions were excluded from clinical trials and their eligibility for the misoprostol alone regimen is unknown.

  • Uterine/genital infection
  • Coagulopathy
  • Hypertension
  • Severe Anemia
  • Cardiovascular disease
  • Cerebrovascular disease


If you have questions about medication abortion, please visit our page on frequently asked questions.

Please contact us with suggestions, updates, or link requests at medicationabortion@ibisreproductivehealth.org

Your access and use of this website is subject to certain terms of use. By viewing web pages in this site, you accept, without limitation or qualification, these terms. Read our privacy statement.

Last updated: September 2009